Richard Gandour

Professor

Organic Chemistry

 

Research Interests

Our most recent work focuses on (1) design and synthesis of affordable anti-infectives and (2) modification of metal oxide surfaces in designing bionano-constructs and responsive thin films.

  1. Williams, A. A.; Day, B. S.; Kite, B. L.; McPherson, M. K.; Slebodnick, C.; Morris, J. R.; Gandour, R. D. Homologous, Long-chain Alkyl Dendrons Form Homologous Thin Films on Silver Oxide Surfaces. Chem. Commun. 2005, 5053-5055. doi:10.1039/b506710c.

  2. Karlovska, J.; Williams, A. A.; Macri, R. V.; Gandour, R. D.; Funari, S. S., Uhrikova, D.; Balgavy, P. Synchrotron SAX and WAX diffraction study of a hydrated very long-chain, dendritic amphiphile+DPPC mixture. Coll. Surf., B. 2007, 54, 160-164. doi:10.1016/j.colsurfb.2006.10.009.

  3. Williams, A. A.; Sugandhi, E. W.; Macri, R. V.; Falkinham, J. O., III; Gandour, R. D. Antimicrobial Activity of Long-Chain, Water-Soluble, Dendritic Tricarboxylato Amphiphiles. J. Antimicrob. Chemother. 2007, 51, 451-458. doi:10.1093/jac/dkl503.

  4. Sugandhi, E. W.; Macri, R. V.; Williams, A. A.; Kite, B. L.; Slebodnick, C.; Falkinham, J., III; Esker, A. R.; Gandour, R. D. Synthesis, Critical Micelle Concentrations, and Antimycobacterial Properties of Homologous, Dendritic Amphiphiles. Probing Intrinsic Activity and the "Cutoff" Effect. J. Med. Chem. 2007, 50, 1645-1650. doi:10.1021/jm061240d.

  5. Sugandhi, E. W.; Falkinham, J. O., III; Gandour, R. D. Synthesis and Antimicrobial Activity of Symmetrical Two-tailed Dendritic Tricarboxylato Amphiphiles. Bioorg. Med. Chem. 2007, 15, 3842-3853. doi:10.1016/j.bmc.2007.03.017.

  6. Sugandhi, E. W.; Slebodnick, C.; Falkinham, J., III; Gandour, R. D. Synthesis and antimicrobial evaluation of water-soluble, dendritic derivatives of epimeric 5-a-cholestan-3-amines and 5-a-cholestan-3-yl aminoethanoates. Steroids 2007, 72, 615-626. doi:10.1016/j.steroids.2007.04.001

  7. Macri, R. V.; Karlovska, J.; Doncel, G. F.; Du, X.; Maisuria, B. B.; Sugandhi, E. W.; Williams, A. A.; Falkinham, J. O., III; Esker, A. R.; Gandour, R. D. Comparing Anti-HIV, Antibacterial, Antifungal, Micellar, and Cytotoxic Properties of Tricarboxylato Dendritic Amphiphiles. Bioorg. Med. Chem. 2009, 17, 3162-3168. dx.doi.org/10.1016/j.bmc.2009.02.055.
  • Professor Emeritus, Louisiana State University, 1993–present
  • Fellow, AAAS
  • B.S. Wheeling Jesuit College, 1967
  • Ph.D. Rice University, 1972
  • Postdoctoral Fellow, University of Kansas, 1971–1975
Richard Gandour

Contact

Email: gandour@vt.edu
Office: 1103 Hahn Hall South
Phone: 540-231-3731

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